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The Comanche Nation Child Care centers mission is to support their respective surrounding communites with child development services.

The Comanche Nation Outreach office in OKC mission is to assist our Comanche tribal members in the OKC and surrounding areas with services provided by the Comanche Nation of Oklahoma.

Our mission is to provide the highest quality of life for our Comanche Nation Tribal members in the years to come through a better vision

 Comanche Nation Prescription Assistance's mission is to provide tribal members with assistance to acquire prescribed medicines, devices, and dental needs.

The mission of the Comanche Nation Prevention & Recovery program is to support Native Americans of all ages in living a life free of dependence of alcohol, tobacco, drugs, gambling, self-destructive, addictive, and abusive behaviors by integrating substance abuse and mental health approaches.

Property & Procurement's mission is to provide efficient and uniform procurement processes in support of the Comanche Nation.

To inform the Comanche Nation membership of the latest activities of the nation and to serve as a social outlet for current affairs and historical data.

The Realty Office provides the Comanche Nation with assistance in all real estate matters.

To reintegrate Comanche tribal members into mainstream society who have been recently released from DOC custody.

It is the mission of the Comanche Nation Social Services Department to provide emergency and general assistance to eligible Comanche tribal members.